Aggiornamenti sull'Ebola — ultimi rapporti e cronologia

North Kivu, 14–19 June: 17 new confirmed cases and 11 deaths (the difference between INSP reports N°30 and N°36), taking the province to 79 cases and 45 deaths.

On 1 June Médecins Sans Frontières announces it is building a 65-bed Ebola treatment centre in Ituri and supporting health facilities in Bunia; by 16 June MSF has three treatment centres operating, in Bunia, Goma and Mongbwalu. Funding is moving too: on 1 June CEPI announces money to fast-track three vaccine candidates (IAVI $3.2 million, Moderna $50 million, University of Oxford $8.6 million), after the UK committed up to £20 million on 21 May, the US State Department $112 million a week later and the European Union €15 million.

Ituri, 6–13 June: 257 new confirmed cases and 76 deaths (the difference between INSP reports N°22 and N°30), taking the province to 717 cases and 146 deaths.

North Kivu, 6–13 June: 37 new confirmed cases and 19 deaths (the difference between INSP reports N°22 and N°30), taking the province to 62 cases and 34 deaths.

Uganda reaches 19 confirmed cases and two deaths as of 6 June, ten more cases and one more death than on 29 May.

Ituri, 30 May – 5 June: 215 new confirmed cases and 35 deaths (the difference between INSP reports N°15 and N°22), taking the province to 460 cases and 70 deaths.

North Kivu, 30 May – 5 June: 10 new confirmed cases and 9 deaths (the difference between INSP reports N°15 and N°22), taking the province to 25 cases and 15 deaths.

Ituri, 19–29 May: 215 new confirmed cases and 31 deaths (the difference between INSP reports N°4 and N°15), taking the province to 245 cases and 35 deaths.

North Kivu, 19–29 May: 12 new confirmed cases and 6 deaths (the difference between INSP reports N°4 and N°15), taking the province to 15 cases and 6 deaths.

South Kivu, 19–29 May: 3 confirmed cases and 1 death, all in Miti-Murhesa health zone (the difference between INSP reports N°4 and N°15). They remain the province's only cases (INSP N°119).

Uganda reaches nine confirmed cases, including one death, as of 29 May: seven more than at WHO's 21 May update.

On 22 May WHO assesses the risk posed by the outbreak as very high at the national level in the DRC, high at the regional level and low globally. The same day the IHR Emergency Committee, first convened by the Director-General on 19 May, issues its temporary recommendations to States Parties.

Ituri, 15–18 May: 22 new confirmed cases and no deaths (the difference between INSP reports N°1 and N°4), taking the province to 30 cases and 4 deaths.

North Kivu, 15–18 May: the province's first 3 confirmed cases, in the Goma, Katwa and Butembo health zones, and no deaths (the difference between INSP reports N°1 and N°4).

After consulting the States Parties where the event is occurring, the WHO Director-General determines on 17 May that Ebola disease caused by Bundibugyo virus in the DRC and Uganda constitutes a Public Health Emergency of International Concern (PHEIC) under the International Health Regulations (2005). Response measures include rapid response teams, medical supplies, strengthened surveillance, laboratory confirmation and infection prevention and control.

Uganda confirms two cases imported from the DRC: an elderly man who died in Kampala on 14 May and was confirmed on 15 May, and a second, unrelated case confirmed on 16 May.

The DRC Ministry of Public Health declares its 17th Ebola outbreak, in the Rwampara, Mongbwalu and Bunia health zones. As of 15 May a total of 246 suspected cases and 80 deaths (four among confirmed cases) are reported from those three Ituri health zones — Rwampara (six health areas affected), Mongbwalu (three) and Bunia. Uganda confirms an outbreak the same day after identifying an imported case. Case fatality in the two earlier Bundibugyo outbreaks, in Uganda in 2007 and the DRC in 2012, ranged from about 30% to 50%, and unlike Zaire ebolavirus there is no licensed vaccine or specific therapeutic for Bundibugyo virus.

At the Institut National de Recherche Biomédicale (INRB) in Kinshasa, eight of the 13 samples sent from Ituri test positive for Ebola disease on 14 May, and the strain is identified as Bundibugyo — the DRC's 17th Ebola outbreak. Preliminary tests in Bunia had been negative for Zaire ebolavirus, dengue, rotavirus, cholera, malaria, plague, mpox and COVID-19.

Ituri, to 14 May: the outbreak's first 8 confirmed cases, 4 of them fatal, in the Mongbwalu, Rwampara and Bunia health zones (INSP report N°1).

WHO receives an alert on 5 May about an unknown illness with high mortality in Mongbwalu Health Zone, Ituri Province, including four health workers who died within four days. The first currently known suspected case, a health worker, had symptom onset on 24 April and died at a medical centre in Bunia. Twenty samples tested at the provincial public health laboratory in Bunia are negative for Ebola (Zaire) virus, so samples are sent to INRB in Kinshasa. By 15 May, 24 suspected cases are in isolation across the Rwampara, Mongbwalu and Bunia health zones.