Aggiornamenti sugli hantavirus — ultimi rapporti e cronologia

ECDC's 14 May daily situation update holds the cluster at 8 confirmed + 2 probable + 1 inconclusive (11 total, 3 deaths, CFR ~27%) — 'no new cases or deaths have been reported since the previous update'. EU/EEA general-population risk reaffirmed VERY LOW. The agency confirms no signal of community transmission in any EU/EEA Member State receiving Hondius returnees and notes 116 disembarked travellers and crew remain on 42-day active monitoring across the 23 host countries. Tristan da Cunha sample shipment via Cape Town for the only outstanding probable (Case 8) is still in transit; ECDC's Public Health Emergency team remains seconded to Spain's CCAES and to the Dutch RIVM through the Rotterdam disinfection phase.

ECDC releases a standalone technical document 'Laboratory testing of Andes virus (ANDV) for high-risk contacts' for EU/EEA reference laboratories on 14 May. The guidance formalises the PCR-on-arrival, day-7 and day-14 schedule used by Spain's Centro Nacional de Microbiología, France's CNR Hantavirus (Institut Pasteur) and Italy's INMI Spallanzani during the Hondius cohort run; recommends serology (IgM/IgG) at day-21 and day-42 as confirmatory; and clarifies the ECDC case definition for probable vs inconclusive — a distinction that has driven this week's reclassification of the U.S. UNMC asymptomatic American (Kornfeld) and held the Italian Spallanzani Calabrian out of the confirmed column.

CDC incident manager for hantavirus Dr David Fitter briefs reporters by phone on the morning of 14 May: 41 persons under U.S. active monitoring — 16 UNMC National Quarantine Unit MV Hondius repatriates, 2 Emory University Hospital repatriates, 7 cruise passengers who disembarked before the outbreak was declared, and 16 flight or close-contact exposures. 11 state health departments are tracking a combined 23 asymptomatic individuals — Arizona, California, Georgia, Kansas, Maryland, Minnesota, Nebraska, New Jersey, Texas, Virginia and Washington — and North Dakota DH has added 5 more residents exposed overseas to a confirmed cruise patient. 'No Americans are positive for hantavirus at this time,' Fitter says; the Level-3 emergency response stays open through the 42-day window.

CDC refreshes the 'Andes virus outbreak on a cruise ship — current situation' page on the afternoon of 14 May to lock the figures Fitter announced in his morning briefing: 41 persons under U.S. monitoring across 12 state health departments; no domestically acquired Andes virus cases in the U.S.; pandemic risk extremely low. The page adds a new FAQ block linking to the IDPH Winnebago County notice to disambiguate the unrelated North-American-strain case in Illinois from the cruise cluster, and cross-references the CDC HAN00528 PPE / airborne-isolation clinical guidance for any future exposed-contact admissions through the 42-day window.

North Dakota Department of Health & Human Services confirms in coordination with the CDC that it is actively monitoring 5 state residents who were exposed overseas to a confirmed MV Hondius hantavirus case — not Hondius passengers themselves, but close contacts of one of the European confirmed cases during a documented out-of-country meeting in early May. All 5 are asymptomatic, isolating at home in three counties (Cass, Burleigh and Grand Forks) under daily symptom logs to NDDHHS through the 42-day window. The addition lifts the U.S. state-monitoring footprint to 12 jurisdictions and 28 individuals; NDDHHS reiterates that the community risk in North Dakota remains very low.

Public Health Wales issues a 14 May statement confirming it is working with the Welsh Government, UKHSA and the four other UK public-health agencies to support 'a small number of Welsh residents' linked to the MV Hondius outbreak who have returned home from the Arrowe Park staggered discharge or from earlier disembarkations. All Welsh residents under PHW oversight are well and asymptomatic; each receives regular precautionary PCR testing plus a daily clinical assessment for the duration of their 45-day self-isolation. PHW emphasises that there are no known hantavirus cases in Wales and that the risk to the general public is very low.

Santé publique France publishes its 14 May situation point: all 26 KL592 / Bichat-repatriation high-risk contacts traced and tested in France have returned PCR-negative on first-round sampling, including the four Le Bourget repatriates still under 15-day Bichat isolation and the 22 KL592 secondary contacts in supervised home or hospital quarantine. The Bichat-confirmed patient (Case 9) remains the only French confirmed case and continues on veno-arterial ECMO at Bichat–Claude Bernard Hospital — Dr Xavier Lescure tells Le Figaro the patient is 'haemodynamically holding' through the 24-hour mark, with the prognosis still guarded but no further deterioration since cannulation on 13 May.

UKHSA and Wirral University Teaching Hospital complete the planned 72-hour supervised observation of the 22 Britons, the 1 UK-resident German national and the 1 Japanese passenger flown back on the 10 May Manchester repatriation. The cohort begins ground-transport home discharge over 13–14 May to 45-day UKHSA-supervised home self-isolation — a tailored daily-clinician package with courier PCR at day 7 and day 14. UKHSA Director-General Prof Susan Hopkins: 'They arrived healthy and asymptomatic and remain so.' UKHSA's England, Scotland, Wales (PHW) and Northern Ireland (PHA) public-health agencies coordinate destination handover; no Briton tests positive on the Arrowe Park discharge PCR.

RIVM's 14 May situation page logs MV Hondius on day 3 of its passage to Rotterdam (ETA evening of 17 May, alternatively morning of 18 May depending on Bay of Biscay weather) with skeleton crew of 25 + 2 RIVM medics aboard; all 27 remain asymptomatic on the daily satellite symptom log. Boluda Towage confirms the Waalhaven berth and BSL-3 disinfection plan with GGD Rotterdam-Rijnmond and the Port Health Authority. The Filipino crew cohort in GGD-arranged Eindhoven quarantine is at day-3 PCR-negative across all 38 contacts; the 12 Radboudumc staff in 6-week preventive quarantine remain asymptomatic on day 7.

Tierra del Fuego Provincial Health official Juan Petrina confirms in a 14 May press briefing in Ushuaia that the Argentine multidisciplinary scientific expert team — virologists, mammalogists and field epidemiologists drawn from the Instituto Malbrán, INTA and CONICET — will arrive in the province 'next week' to capture and test rodents at the municipal landfill and along the index couple's pre-cruise birdwatching itinerary. Petrina says results are expected within ~4 weeks. The province continues to push back on the landfill-origin framing as a 'smear campaign' and asks national authorities to treat the working hypothesis cautiously until trap data are in.

CNBC publishes a 14 May synthesis 'The hantavirus outbreak isn't another COVID — but experts say it's testing U.S. readiness.' Coverage anchors on Dr David Fitter's morning briefing (41 under U.S. monitoring, 12 state DHs engaged) and Michael Osterholm's CIDRAP read that the next 24 hours of the 42-day window are 'the early flank, not the test.' CNBC notes the Bichat ECMO patient remains the only critically ill case worldwide and that no new lab-confirmed cases have emerged since 13 May 14:00 CEST. Investor framing: airline and Antarctic-charter equities (Oceanwide is privately held) traded flat; the wider outbreak-preparedness portfolio (BioFire, T2 Biosystems, Inovio) outperformed.

WHO Director-General Dr Tedros Adhanom Ghebreyesus publishes a follow-up video message to the people of Tenerife on 14 May. Tedros thanks Canarian authorities, Cruz Roja Tinerfeña and the Spanish ministerial team for closing out the Granadilla disembarkation 'without a single onward community case so far' and confirms the WHO operational presence in Spain has been formally stood down. He frames the Hondius response as 'the cleanest live exercise of the post-2024 IHR amendments to date' and reiterates that the long incubation window means 'we are still very far from the all-clear' — 42-day active monitoring of repatriated travellers and crew continues through 22 June.

Public Health Scotland publishes a 14 May statement (re-syndicated by STV, GB News and Yahoo News UK on 15 May) confirming it is working with UKHSA and the four other UK public-health agencies to follow up with 'a small number of individuals' in Scotland who may have had contact with confirmed MV Hondius hantavirus cases. Scottish contacts will receive precautionary testing plus ongoing clinical and welfare support for up to 45 days from last potential exposure under daily NHS-board oversight. PHS Director of Public Health Science Prof Nick Phin: 'There are currently no known cases of hantavirus in Scotland and the risk to the general public is very low.'

Emory University Hospital and the U.S. Department of Health and Human Services confirm on 13 May that the mildly symptomatic MV Hondius passenger transferred from Offutt on 11 May has tested PCR-negative for Andes hantavirus on serial sampling at the Serious Communicable Diseases Unit. The patient is downgraded out of biocontainment to a single-occupancy observation room for the remainder of the 21-day Georgia-DPH supervised quarantine; the asymptomatic close contact remains in adjoining evaluation under daily symptom checks. HHS Secretary frames the result as 'reassuring but not a clearance' given the 42-day incubation window.

CIDRAP (University of Minnesota) publishes its 13 May synthesis of the outbreak: cluster holds at 11 cases (9 confirmed + 2 probable) with 3 deaths, CFR ~27%. Director Michael Osterholm tells media the post-COVID public-health response has been 'textbook' — sealed transfers, biocontainment quarantine, day-7 and day-14 PCR — but cautions that 'the 42-day incubation window is the real test, not the next 24 hours'. CIDRAP confirms 116 disembarked travellers and crew remain under monitoring across 23 countries, with no community-transmission signal in any host nation.

Dr Xavier Lescure, infectious-disease lead at Bichat–Claude Bernard Hospital, briefs French media on 13 May that the confirmed Hondius patient has been placed on veno-arterial ECMO after fulminant cardio-pulmonary failure overnight. Lescure calls the manoeuvre 'the final stage of supportive care' and tells reporters 'her prognosis is compromised and the next hours will be determinative.' Health Minister Stéphanie Rist confirms the four other Bichat returnees remain PCR-negative and that all 22 KL592 secondary contacts in France are now hospitalised or under fiduciary quarantine.

INMI Lazzaro Spallanzani issues a 13 May bulletin confirming that biological samples from the 25-yo Calabrian KL592 contact have arrived at its BSL-4 virology laboratory and are being run on the European Reference Laboratory network's Andes virus PCR + serology panel. The hospital says preliminary results are expected within 24–48 hours and that the patient remains symptomatic but clinically stable in the high-containment ward. The Ministero della Salute keeps the three other Italian KL592 passengers (Lombardy, Lazio, Calabria) under regional active surveillance.

ECDC's 13 May daily situation update holds the cluster at 9 confirmed + 2 probable (11 total, 3 deaths, CFR ~27%) with no new laboratory positives in the last 24h. The agency reiterates EU/EEA general-population risk as VERY LOW and notes 'no signal of community transmission' in any Member State receiving Hondius returnees. ECDC asks Member States to keep 42-day active monitoring of all returnees and contacts, and confirms its Public Health Emergency team remains seconded to Spain's CCAES and to the Dutch RIVM through the disinfection phase.

RIVM publishes its 13 May situation page: MV Hondius is on day 2 of its passage to Rotterdam (ETA evening of 17 May) with a skeleton crew of 27 plus 2 RIVM medics aboard, all in onboard quarantine and submitting daily symptom logs by satellite. Rotterdam Port Health and GGD Rotterdam-Rijnmond have approved a sealed berth at Waalhaven for full disinfection by Boluda Towage under BSL-3 protocols; crew will disembark directly into supervised 42-day quarantine at a dedicated GGD facility before any onward travel.

WHO incident-management lead Dr Diana Rojas Alvarez updates Geneva-based reporters on 13 May: the cluster remains at 11 cases (9 confirmed + 2 probable) and 3 deaths, with the French Bichat patient now on ECMO the only critically ill case. WHO reiterates that 'the risk to the wider public remains low' and confirms the Saint Helena resident remains a probable case under island isolation pending sample transport. The agency notes 42-day active monitoring of 116 disembarked travellers across 23 countries continues without new symptomatic alerts.

CDC refreshes its 'Andes virus outbreak on a cruise ship — current situation' page on 13 May: no new U.S. cases since the 11 May Nebraska Biocontainment Unit positive; the asymptomatic American remains clinically stable on day-2 of supportive observation. HHS confirms the Emory University Hospital symptomatic transfer has tested PCR-negative for Andes virus and is being downgraded to observational care. CDC keeps the Level-3 emergency response open and adds Kansas, Minnesota and Washington state to the active-monitoring list (now 12 states) after KL592 manifest review surfaced two King-County, WA passengers seated within two rows of Case 2 on the 25 Apr JNB–AMS leg.

Italy's Ministero della Salute confirms in a 13 May afternoon statement (carried by LaPresse and the Reuters wire) that the BSL-4 Andes-virus PCR + serology panel run at INMI Lazzaro Spallanzani on the 25-year-old Calabrian KL592 contact has returned NEGATIVE. The same statement clears three further Italian suspects processed at Ospedale Luigi Sacco, Milan — an Argentine tourist with pneumonia in Messina, a British tourist hospitalised in Milan, and the Briton's travelling companion. Health Minister Orazio Schillaci keeps the three remaining Italian KL592 passengers (Lombardy, Lazio, Calabria) under 42-day regional active surveillance and asks GPs to maintain Andes-virus differential vigilance.

Spanish Health Minister Mónica García briefs media on 13 May afternoon: the 13 asymptomatic Spanish passengers in supervised quarantine at the Hospital Central de la Defensa Gómez Ulla have all returned NEGATIVE PCR results on a second-round sample run by the Centro Nacional de Microbiología. A third PCR is scheduled for Sunday 17 May; if negative, isolation conditions will be relaxed to allow supervised family visits and common-area movement. The Spanish confirmed-positive passenger remains 'estable y con pocos síntomas' on supplemental oxygen begun Sunday night — slightly improved over the 12 May status, with no progression to critical care.

Bichat–Claude Bernard Hospital tells the Reuters wire on 13 May afternoon that the Hondius confirmed patient on veno-arterial ECMO is 'haemodynamically holding' through the first 12 hours of cannulation; Dr Xavier Lescure's team reiterates the prognosis remains 'guarded' and the next 24 hours are determinative. Santé publique France confirms the four other Bichat returnees have completed a third PCR — all negative — and 21 of the 22 KL592 secondary contacts in France are PCR-negative on first-round sampling. Health Minister Stéphanie Rist reaffirms 15-day Bichat isolation and 42-day home active monitoring.

ECDC strain-analysis update circulated to EU/EEA Member States and quoted in Euronews on 13 May afternoon: ANDV genomes sequenced from all 8 confirmed Hondius patients to date are 'virtually identical' (≥99.9% nucleotide identity), confirming the Palacios virological.org preliminary read and ruling out a mutation event. ECDC reads this as a single zoonotic spillover near Ushuaia followed by limited human-to-human transmission aboard MV Hondius, not ongoing rodent-source reintroduction. Onward sustained transmission outside the cluster is considered very unlikely; routine ANDV-PCR added to all EU/EEA Hondius-returnee panels.

ECDC's 14:00 CEST cut-off situation update on 13 May reclassifies one previously-confirmed case as inconclusive pending repeat testing, leaving the cluster at 8 confirmed + 2 probable + 1 inconclusive + 3 deaths (10 total, CFR ~30%). 'No new cases or deaths have been reported since the previous update.' EU/EEA general-population risk reaffirmed VERY LOW. ECDC asks Member States to continue 42-day active monitoring and reports that the Italian Spallanzani PCR-negative result removes the only outstanding KL592 suspect from the European pending column; Tristan da Cunha sample shipment remains in transit.

European Commissioners Hadja Lahbib (Preparedness & Crisis Management) and Joseph Sikela (International Partnerships) host a Brussels coordination meeting on the afternoon of 13 May to push for tighter EU-wide alignment of cruise-ship quarantine protocols after the Hondius response exposed wide variation — Spanish and French nationals went to military and high-containment hospitals, Dutch and Belgian nationals to home isolation. Lahbib: 'Health threats can easily cross borders, and that is why coordination is key.' Sikela calls the outbreak a reminder 'of our vulnerability when it comes to health' and announces an HSC follow-up meeting on 20 May.

Oceanwide Expeditions tells the Associated Press on 13 May afternoon (wire updated 15:56 CEST) it will provide 'clarity on whether the vessel will sail, and the sailing schedule, by the end of this week'. The operator confirms MV Hondius is on day 2 of its passage to Rotterdam with 25 working crew, 2 RIVM medics and the body of the deceased German passenger aboard, ETA 17–18 May. All summer-season Antarctic charters remain provisionally suspended pending a joint Boluda Towage / RIVM / GGD Rotterdam-Rijnmond BSL-3 disinfection audit at Waalhaven; bookings will be honoured on the sister vessel MV Plancius or rolled to 2027.

UKHSA and Wirral University Teaching Hospital begin the staggered discharge of the 22 Britons, 1 UK-resident German national and 1 Japanese passenger from Arrowe Park's self-contained flats on the afternoon of 13 May, after completing the planned 72-hour in-hospital supervised observation. Each returnee receives a tailored UKHSA support package — daily health-team contact, on-call clinician, courier PCR at day 7 and day 14, no public transport — for the remaining ~42 days of home isolation. UKHSA Chief Scientific Officer Prof Robin May: 'They arrived healthy and asymptomatic and remain so.'

UKHSA confirms via UPI / STV wire on 13 May afternoon that the UK is airlifting 10 British contacts (8 Saint Helena disembark passengers + 2 Hondius crew) from Saint Helena and Ascension Island to UK self-isolation facilities offering specialist medical services. RAF Voyager + RAF C-17 chartered for the staged move; arrival expected at Brize Norton over 14–16 May. UKHSA: 'We are moving some contacts who are already isolating to places where they can safely self-isolate with access to appropriate specialist medical services.' 4 British nationals will remain on Saint Helena at the islanders' request.

Argentina's Ministerio de Salud announces on the afternoon of 13 May, via NPR-carried wire, that a multidisciplinary scientific expert team — virologists, mammalogists and field epidemiologists drawn from the Instituto Nacional de Enfermedades Infecciosas Dr. Carlos G. Malbrán, INTA and CONICET — will be dispatched 'in the coming days' to characterise the suspected MV Hondius exposure site at the Ushuaia municipal landfill. The mission will trap and screen rodents, sample soil and water, and re-walk the index couple's pre-cruise birdwatching itinerary. PAHO Director Jarbas Barbosa confirms regional technical-cooperation funding.

PHAC and provincial authorities give CP24 a 13 May Canada-wide roundup: 10 active contacts under monitoring — 6 MV Hondius passengers + 4 KL592 flight-exposure contacts. Breakdown: 4 on Vancouver Island (a Yukon couple in their 70s, one Vancouver Islander in their 70s, one BC-origin returnee now resident abroad), 2 in Grey Bruce (Ontario), 1 in Peel (Ontario), 2 in Alberta and 1 in Quebec (downgraded to low-risk). 7 further Ontario residents flagged on 12 May continue voluntary isolation. PHAC NML lead Dr David Safronetz: 'It isn't the next pandemic … this isn't COVID.' All 10 remain asymptomatic at day-3 PCR.

University of Nebraska Medical Center and the U.S. CDC confirm late on 13 May (21:37 ET / 03:37 CEST 14 May) that Dr Stephen Kornfeld — the MV Hondius ship's doctor, originally admitted to the Nebraska Biocontainment Unit on a faintly-positive shipboard nasal swab — has tested PCR-NEGATIVE on UNMC's confirmatory Andes-virus panels. Kornfeld is transferred out of biocontainment to join the 15 other Americans in the National Quarantine Unit; all 16 remain asymptomatic. UNMC notes the original sample was twice re-tested in the Netherlands with one positive and one negative read. The retraction removes the only U.S. confirmed Andes-virus case; CDC keeps its Level-3 response open through the 42-day window.

TODAY / The Hill / Fox 5 DC / Boston.com / KGW / ABC11 wire round-up overnight: U.S. state-level monitoring footprint expands beyond the 12 CDC-listed states to include North Carolina (NCDHHS — one resident at UNMC), Maryland (two KL592 flight-exposure contacts in passive surveillance), Massachusetts (Boston travel influencer Jake Rosmarin at UNMC), Oregon (a Bend-based physician at UNMC) and New Hampshire (two state-tied residents in passive surveillance). All contacts remain asymptomatic on day-3 PCR; CDC and state DHs reiterate the U.S. public-health risk remains extremely low and that monitoring follows the 42-day active surveillance protocol.

Spain's Health Secretary Javier Padilla updates La Moncloa correspondents late on 13 May (22:00 CEST): the Andes-positive Spanish national isolated in the High-Level Isolation and Treatment Unit (UATAN) at the Hospital Central de la Defensa Gómez Ulla continues 'estable y con pocos síntomas' on supplemental oxygen, with Padilla saying he expects the patient to 'evolve in a totally favorable manner.' The 13 Spanish co-passengers all returned NEGATIVE on the second-round PCR run by the Centro Nacional de Microbiología; a third PCR is scheduled for Sunday 17 May before any relaxation of in-hospital isolation conditions, with 42-day active monitoring continuing through 17 June.

Oceanwide Expeditions tells PBS NewsHour in a 13 May evening interview that a final go/no-go on the MV Hondius summer season will be issued 'by the end of this week' once the joint Boluda Towage / RIVM / GGD Rotterdam-Rijnmond BSL-3 disinfection audit at Waalhaven is complete. The operator confirms the ship is on day 2 of its passage to Rotterdam (skeleton crew of 25 + 2 RIVM medics + the body of the deceased German passenger aboard), and that all summer 2026 Antarctic charter bookings have been provisionally re-allocated to the sister vessel MV Plancius or rolled to 2027 — passengers will be contacted by the operator's customer-service team within 48 hours of the audit outcome.

UN News carries WHO Director-General Tedros Adhanom Ghebreyesus's 13 May Geneva briefing: 'We can say confidently that this phase of the operation was successful.' Nearly 150 passengers and crew from 23 countries were disembarked over two days from MV Hondius via nine charter flights arranged by eight countries — no commercial flights used. WHO mandates active monitoring and 42-day quarantine for all repatriated passengers and crew from 10 May, with each host country reporting regularly through the IHR network. Tedros: 'There is no sign that we are seeing the start of a larger outbreak,' but cautions the situation could change given the virus's long incubation window.

Australian Defence Force-chartered medevac jet from Tenerife (departed 11 May) lands at RAAF Pearce / Perth on the morning of 12 May with 4 Australians, 1 Australian permanent resident, 1 British national resident in Australia and 1 New Zealander. Contagion Class biocontainment pods used in-flight; passengers transferred under ambulance escort to the Bullsbrook Defence Training Centre quarantine compound ~40 km north-east of Perth. Health Minister Mark Butler calls it 'one of the stronger responses globally'. The NZ government negotiates onward transfer of the New Zealander with NZ's Ministry of Health, led by Dr Corina Grey.

WHO's epidemic-and-pandemic-preparedness lead Dr Maria Van Kerkhove and incident manager Dr Diana Rojas Alvarez brief reporters in Geneva: 11 cases total (9 laboratory-confirmed + 2 probable; the French Bichat woman and the Spanish Gómez Ulla case were elevated overnight from preliminary to confirmed after Santé publique France and the Centro Nacional de Microbiología completed sequencing), 3 deaths, CFR ~27%. WHO Director-General Tedros: 'The ship still has around 30 people — the crew and two health workers — and they will need our support throughout their journey until they reach Rotterdam.' WHO reiterates that risk to the general public globally remains low.

Joint Madrid press conference at La Moncloa: Spanish Prime Minister Pedro Sánchez and WHO Director-General Tedros confirm the outbreak total at 11 (9 confirmed + 2 probable) with 3 deaths and declare the Tenerife evacuation 'a success.' Tedros: 'There is no sign that we are seeing the start of a larger outbreak,' but 'our work is not over' — the 30-person Hondius skeleton crew, the disembarked contacts and the Saint Helena cohort still need 42-day active monitoring. Sánchez frames the Spanish response as 'legal responsibility and moral obligation' and warns 'the world does not need more selfishness or more fear.'

A 25-year-old Calabrian man already in precautionary quarantine — one of four Italian tourists flagged by the Ministero della Salute as KLM KL592 contacts of the late Case 2 — develops fever and respiratory symptoms and is transferred to INMI Lazzaro Spallanzani in Rome, Italy's national reference hospital for high-consequence infectious diseases. Samples are couriered to Spallanzani's BSL-4 lab; PCR pending. The other three Italian KL592 passengers remain under active monitoring by the regional health authorities of Lombardy, Lazio and Calabria.

California Department of Public Health and the Santa Clara County Public Health Department confirm that a South Bay resident — one of four Californians flagged as Saint Helena-disembark contacts of MV Hondius — is at home and being actively monitored. The resident is asymptomatic and tests provisionally negative on day-7 PCR; the standard 42-day active surveillance with daily symptom checks runs through the third week of June. Officials repeat the CDC line that the U.S. public-health risk remains extremely low.

CDC publishes its standing 'Andes virus outbreak on a cruise ship — current situation' page (refreshed 12 May): no domestically acquired Andes virus cases in the United States, pandemic risk assessed as extremely low. The agency confirms the 17 Offutt/UNMC evacuees plus the two Emory transfers remain the only U.S. repatriation cohort, and reiterates that all exposed travellers — including the Saint Helena disembark in Santa Clara County — are under public-health monitoring through state and local health departments.

The Philippine Embassy in The Hague and DFA Manila confirm that 17 additional Filipino crew members from MV Hondius landed at Eindhoven Air Base on the night of 12 May and were transferred under sealed convoy to GGD-arranged accommodation for a 42-day quarantine. This raises the Filipino crew cohort in Dutch quarantine to 38 (21 already in country plus the 17 newcomers). DutchNews.nl confirms the second Eindhoven flight closes out passenger and crew repatriation from Tenerife — only the Hondius skeleton crew of 27 plus 2 RIVM medics remain at sea.

Public Health — Seattle & King County announces three King County residents are now under active hantavirus monitoring tied to the MV Hondius outbreak. Two were seated within two rows of Case 2 on the 25 April KLM/Airlink leg from Johannesburg to Amsterdam and are isolating asymptomatically at home in coordination with the Washington State Department of Health. A third — a King County resident who travelled on the Hondius — remains under observation at the UNMC National Quarantine Unit. Officials repeat that community risk in King County remains low and that no cases have been identified in Washington state.

Minnesota Department of Health, supported by Michael Osterholm's CIDRAP team at the University of Minnesota, confirms it is actively monitoring one Minnesotan who 'may have briefly been exposed overseas' to a person who later tested positive for Andes virus aboard MV Hondius. The contact — not a Hondius passenger themselves — is asymptomatic, isolating at home, and submitting daily symptom logs to MDH; Minnesota becomes one of several Midwest states (alongside Kansas, where KDHE is tracking three high-risk contacts) folded into the expanded U.S. state monitoring footprint.

Illinois Department of Public Health (IDPH) confirms in a 12 May notice — picked up nationally on 14 May — that it is investigating a potential hantavirus case in a Winnebago County resident with NO link to the MV Hondius cruise ship outbreak. The patient is recovering from mild symptoms after cleaning a home with rodent droppings and did not require hospitalisation; commercial antibody serology was reactive, with CDC confirmatory testing up to 10 days out. IDPH stresses the implicated strain is a North-American hantavirus (Sin Nombre virus is the likely culprit) and is NOT known to spread person-to-person. Illinois has recorded only 7 hantavirus cases since 1993.

U.S. State Department / CDC government-charter flight repatriates 17 American passengers from Tenerife to Offutt Air Force Base in the early hours of 11 May, then by ground transport to the University of Nebraska Medical Center. 16 are admitted to the National Quarantine Unit and one faintly-PCR-positive American (the Hondius ship's doctor) is admitted directly to the Nebraska Biocontainment Unit — provisionally the first U.S. Andes-virus case, pending UNMC confirmatory testing. A second symptomatic American (mild) is monitored in the quarantine unit. 42-day active monitoring with daily symptom checks and PCR at day 7 and day 14.

Two of the 17 US returnees are diverted on 11 May from Offutt to Hartsfield–Jackson Atlanta International (~09:00 local) and transported to Emory University Hospital's Serious Communicable Diseases Unit. One symptomatic individual enters the biocontainment unit; the other, an asymptomatic close contact, is in adjoining evaluation rooms. The transfer is a contingency move because UNMC's biocontainment unit has insufficient capacity for the full cohort. By 12 May, U.S. states actively monitoring Hondius returnees and Saint Helena disembarks include Arizona, California, Georgia, Maryland, Nebraska, New Jersey, New York, Texas and Virginia.

Radboudumc announces that 12 staff who treated the 41-year-old Dutch confirmed case (the Hondius ship's doctor) are placed in preventive quarantine for six weeks after the latest international BSL-3/4 procedures for hantavirus blood processing and patient urine disposal were not fully followed. The hospital says infection risk is low but acts out of precaution; RIVM and GGD Gelderland-Zuid oversee monitoring.